Last update 08 Jul 2025

Tiotropium Bromide Monohydrate/Fluticasone Propionate/Salmeterol xinafoate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
SALTIF
Target
GR x M3 receptor x cPLA2α x β2-adrenergic receptor
Action
agonists, antagonists
Mechanism
GR agonists(Glucocorticoid receptor agonists), M3 receptor antagonists(Muscarinic acetylcholine receptor M3 antagonists), cPLA2α agonists(Cytosolic phospholipase A2 agonists)
Therapeutic Areas
Respiratory Diseases
Active Indication-
Inactive Indication
Pulmonary Disease, Chronic Obstructive
Originator Organization
Hanmi Pharmaceutical Co., Ltd.Hanmi Pharmaceutical Co., Ltd.
Active Organization-
Inactive Organization
Hanmi Pharmaceutical Co., Ltd.Hanmi Pharmaceutical Co., Ltd.
License Organization-
Drug Highest PhaseApproved
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC19H24BrNO5S2
InChIKeyMQLXPRBEAHBZTK-SEINRUQRSA-M
CAS Registry411207-31-3
View All Structures (3)

Related

2
Clinical Trials associated with Tiotropium Bromide Monohydrate/Fluticasone Propionate/Salmeterol xinafoate
NCT03395002
/ CompletedPhase 4
Comparison of Bronchodilator Efficacy of Tiotropium/Salmeterol/Fluticasone 9/50/500 mcg Combination Treatment Administered Via Discair® With Original Products Seretide Diskus 500 mcg Inhalation Powder Plus Spiriva 18 mcg Inhalation Powder Treatment in Patients With Moderate-severe Chronic Obstructive Pulmonary Disease (COPD)
NCT00864812
/ CompletedPhase 4
A Randomized, Open Label, Multicenter, Phase 4 Study for the Comparison of Efficacy of Tiotropium Plus Salmeterol/ Fluticasone Propionate Compared With Tiotropium Alone in COPD Patients
100 Clinical Results associated with Tiotropium Bromide Monohydrate/Fluticasone Propionate/Salmeterol xinafoate
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100 Translational Medicine associated with Tiotropium Bromide Monohydrate/Fluticasone Propionate/Salmeterol xinafoate
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100 Patents (Medical) associated with Tiotropium Bromide Monohydrate/Fluticasone Propionate/Salmeterol xinafoate
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100 Deals associated with Tiotropium Bromide Monohydrate/Fluticasone Propionate/Salmeterol xinafoate
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Pulmonary Disease, Chronic ObstructivePhase 3-
Hanmi Pharmaceutical Co., Ltd.Hanmi Pharmaceutical Co., Ltd.
01 Oct 2016
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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