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Last update 04 Jun 2025
Balcinrenone/Dapagliflozin
Last update 04 Jun 2025
Overview
Basic Info
Drug Type Small molecule drug |
Synonyms Balcinrenone/达格列净, Balcinrenone达格列净 |
Target |
Action modulators, inhibitors |
Mechanism MR modulators(Mineralocorticoid receptor modulators), SGLT2 inhibitors(Sodium/glucose cotransporter 2 inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhasePhase 3 |
First Approval Date- |
Regulation- |
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Structure/Sequence
Molecular FormulaC24H35ClO9 |
InChIKeyGOADIQFWSVMMRJ-UPGAGZFNSA-N |
CAS Registry960404-48-2 |
View All Structures (2)
Related
5
Clinical Trials associated with Balcinrenone/DapagliflozinNCT06979388
A Phase I, Randomised, Single-dose, Open-label, 3-period, 3-treatment, 3-way Crossover Study to Assess the Effect of Food on Balcinrenone/Dapagliflozin Pharmacokinetics in Fed and Fasted State and Pharmacokinetics of Balcinrenone When Dosed With a P-gp Inhibitor in Healthy Participants.
CTR20243265
一项在心力衰竭合并肾功能损害患者中 评价 Balcinrenone/达格列净相比达格列净对心力衰竭事件和心血管死亡风险影响的随机、双盲、 III期研究
[Translation] A randomized, double-blind, phase III study evaluating the effects of balcinrenone/dapagliflozin versus dapagliflozin on the risk of heart failure events and cardiovascular death in patients with heart failure and renal impairment
NCT06651021
A Phase I, Open-label Study to Assess the Pharmacokinetics, Safety and Tolerability Following Administration of a Single Dose of Balcinrenone/Dapagliflozin in Healthy Chinese Participants
100 Clinical Results associated with Balcinrenone/Dapagliflozin
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100 Translational Medicine associated with Balcinrenone/Dapagliflozin
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100 Patents (Medical) associated with Balcinrenone/Dapagliflozin
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100 Deals associated with Balcinrenone/Dapagliflozin
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Heart Failure | Phase 3 | United States | 12 Apr 2024 | |
| Heart Failure | Phase 3 | Japan | 12 Apr 2024 | |
| Heart Failure | Phase 3 | Argentina | 12 Apr 2024 | |
| Heart Failure | Phase 3 | Australia | 12 Apr 2024 | |
| Heart Failure | Phase 3 | Austria | 12 Apr 2024 | |
| Heart Failure | Phase 3 | Brazil | 12 Apr 2024 | |
| Heart Failure | Phase 3 | Bulgaria | 12 Apr 2024 | |
| Heart Failure | Phase 3 | Canada | 12 Apr 2024 | |
| Heart Failure | Phase 3 | Chile | 12 Apr 2024 | |
| Heart Failure | Phase 3 | Colombia | 12 Apr 2024 |
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