Last update 30 May 2026

ONO-7018

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
CTX-177, ONO 7018, ONO-7018
+ [1]
Target
MALT1
Action
inhibitors
Mechanism
MALT1 inhibitors(Mucosa-associated lymphoid tissue lymphoma translocation protein 1 inhibitors)
Therapeutic Areas
NeoplasmsImmune System DiseasesHemic and Lymphatic Diseases
Active Indication
B-Cell LymphomaT-Cell Lymphoma
Inactive Indication
B-Cell LeukemiaChronic Lymphocytic Leukemia
Originator Organization
Chordia Therapeutics, Inc.Chordia Therapeutics, Inc.
Active Organization
Ono Pharmaceutical Co., Ltd.Ono Pharmaceutical Co., Ltd.
Inactive Organization-
License Organization
Chordia Therapeutics, Inc.Chordia Therapeutics, Inc.
Ono Pharmaceutical Co., Ltd.Ono Pharmaceutical Co., Ltd.
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with ONO-7018
NCT06622226
/ Active, not recruitingPhase 1
A Phase 1, Open-label, Dose Escalation Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of ONO-7018 in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma (NHL) in Japan
NCT05515406
/ TerminatedPhase 1
A Phase I, Open-label, Dose Escalation Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of ONO-7018 in Patients With Relapsed or Refractory NHL or CLL
100 Clinical Results associated with ONO-7018
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100 Translational Medicine associated with ONO-7018
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100 Patents (Medical) associated with ONO-7018
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100 Deals associated with ONO-7018
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
T-Cell LymphomaPhase 1
Japan
Ono Pharmaceutical Co., Ltd.Ono Pharmaceutical Co., Ltd.
27 Nov 2024
B-Cell LeukemiaPhase 1
United States
Ono Pharmaceutical Co., Ltd.Ono Pharmaceutical Co., Ltd.
13 Feb 2023
B-Cell LymphomaPhase 1
United States
Ono Pharmaceutical Co., Ltd.Ono Pharmaceutical Co., Ltd.
13 Feb 2023
Chronic Lymphocytic LeukemiaPhase 1
United States
Ono Pharmaceutical Co., Ltd.Ono Pharmaceutical Co., Ltd.
13 Feb 2023
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Clinical Result

Indication
Phase
Evaluation
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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