Last update 27 Feb 2026

GLP-1/Dyrk1a ASO conjugate(Ionis Pharmaceuticals)

Overview

Basic Info

Drug Type
ASO, Drug conjugates
Synonyms-
Target
DYRK1A x GLP-1R
Action
inhibitors, agonists
Mechanism
DYRK1A inhibitors(Dual-specificity tyrosine-phosphorylation regulated kinase 1A inhibitors), GLP-1R agonists(Glucagon-like peptide 1 receptor agonists)
Therapeutic Areas
Immune System DiseasesEndocrinology and Metabolic Disease
Active Indication-
Inactive Indication
Diabetes Mellitus, Type 1Diabetes Mellitus, Type 2
Originator Organization
Ionis Pharmaceuticals, Inc.Ionis Pharmaceuticals, Inc.
Active Organization-
Inactive Organization
Ionis Pharmaceuticals, Inc.Ionis Pharmaceuticals, Inc.
License Organization-
Drug Highest PhasePendingPreclinical
First Approval Date-
Regulation-

Structure/Sequence

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Related

100 Clinical Results associated with GLP-1/Dyrk1a ASO conjugate(Ionis Pharmaceuticals)
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100 Translational Medicine associated with GLP-1/Dyrk1a ASO conjugate(Ionis Pharmaceuticals)
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100 Patents (Medical) associated with GLP-1/Dyrk1a ASO conjugate(Ionis Pharmaceuticals)
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100 Deals associated with GLP-1/Dyrk1a ASO conjugate(Ionis Pharmaceuticals)
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetes Mellitus, Type 1Preclinical
United States
Ionis Pharmaceuticals, Inc.Ionis Pharmaceuticals, Inc.
01 Jun 2020
Diabetes Mellitus, Type 2Preclinical
United States
Ionis Pharmaceuticals, Inc.Ionis Pharmaceuticals, Inc.
01 Jun 2020
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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