Last update 21 Nov 2024

Anti-MUC1 CAR-T cell/PD-1 knockout engineered T cell therapy (Guangzhou Anjie Biomedical Technology)

Overview

Basic Info

Drug Type
CAR-T
Synonyms
AntiMUC1 CAR T cells and PD1 knockout engineered T cells, AntiMUC1 CART cells combined with PD1 knockout engineered T cells
Target
MUC1
Mechanism
MUC1 inhibitors(Mucin-1 inhibitors), Gene transference, T lymphocyte replacements
Therapeutic Areas
NeoplasmsSkin and Musculoskeletal Diseases
Active Indication
Advanced breast cancer
Inactive Indication
Esophageal CarcinomaNon-Small Cell Lung Cancer
Originator Organization
Guangzhou Anjie Biomedical Technology Co., Ltd.Guangzhou Anjie Biomedical Technology Co., Ltd.
Active Organization
Guangzhou Anjie Biomedical Technology Co., Ltd.Guangzhou Anjie Biomedical Technology Co., Ltd.
Inactive Organization
University of Technology SydneyUniversity of Technology SydneyThe First Hospital of Hunan University of Chinese Medicine
Drug Highest PhasePhase 1/2
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with Anti-MUC1 CAR-T cell/PD-1 knockout engineered T cell therapy (Guangzhou Anjie Biomedical Technology)
ChiCTR1900025088 / RecruitingEarly Phase 1IIT
Early dose pilot study for MUC1 positive advanced breast cancer treated with pd-1 knockout MUC1 target chimeric antigen receptor T cells (AJMUC1)
NCT05812326 / CompletedPhase 1/2IIT
Exploratory Clinical Study of PD-1 Knockout Targeting MUC1 CAR-T Cells (AJMUC1) in the Treatment of MUC1-positive Advanced Breast Cancer
100 Clinical Results associated with Anti-MUC1 CAR-T cell/PD-1 knockout engineered T cell therapy (Guangzhou Anjie Biomedical Technology)
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100 Translational Medicine associated with Anti-MUC1 CAR-T cell/PD-1 knockout engineered T cell therapy (Guangzhou Anjie Biomedical Technology)
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100 Patents (Medical) associated with Anti-MUC1 CAR-T cell/PD-1 knockout engineered T cell therapy (Guangzhou Anjie Biomedical Technology)
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100 Deals associated with Anti-MUC1 CAR-T cell/PD-1 knockout engineered T cell therapy (Guangzhou Anjie Biomedical Technology)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced breast cancerPhase 2
CN
Guangzhou Anjie Biomedical Technology Co., Ltd.Guangzhou Anjie Biomedical Technology Co., Ltd.
17 May 2019
Esophageal CarcinomaPhase 1
CN
Guangzhou Anjie Biomedical Technology Co., Ltd.Guangzhou Anjie Biomedical Technology Co., Ltd.
15 Sep 2018
Non-Small Cell Lung CancerPhase 1
CN
Guangzhou Anjie Biomedical Technology Co., Ltd.Guangzhou Anjie Biomedical Technology Co., Ltd.
20 Jan 2018
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Clinical Result

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Approval

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Regulation

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