Delving into the Latest Updates on Budesonide/Mesalazine with Synapse

Overview

Basic Info

Drug Type

Small molecule drug

Synonyms-

Target

GR x PP2A

Action-

Mechanism

GR agonists(Glucocorticoid receptor agonists), PP2A inhibitors(Protein phosphatase 2A inhibitors)

Therapeutic Areas-

Active Indication-

Inactive Indication-

Originator Organization

Dr. Falk Pharma GmbH

Active Organization-

Inactive Organization-

License Organization-

Drug Highest Phase-

First Approval Date-

Regulation-

Structure/Sequence

Molecular FormulaC25H34O6

InChIKeyVOVIALXJUBGFJZ-KWVAZRHASA-N

CAS Registry51333-22-3

View All Structures (2)

Transient Tachypnea of the Newborn (TTN) is a common respiratory disorder affecting late preterm and term babies caused by lung edema resulting from delayed absorption of fetal alveolar lung fluid.
The investigators hypothesize that ENAC expression will be up-regulated as a result of administration of corticosteroids. This effect will lead to enhanced absorption of fetal lung fluid finally treating TTN. The aim of our study will be to evaluate whether inhaled corticosteroids reduce respiratory distress and morbidity in late preterm and term neonates presenting with TTN.

Start Date01 Mar 2012

Sponsor / Collaborator