Last update 29 Nov 2025

Anti-HIF-2alpha siRNA therapy (Calando)

Overview

Basic Info

Drug Type
siRNA
Synonyms
CALAA-02
Target
HIF-2α
Action
inhibitors
Mechanism
HIF-2α inhibitors(Endothelial PAS domain-containing protein 1 inhibitors), RNA interference
Therapeutic Areas
NeoplasmsOther Diseases
Active Indication-
Inactive Indication
NeuroblastomaSolid tumor
Originator Organization
Calando Pharmaceuticals, Inc.Calando Pharmaceuticals, Inc.
Active Organization-
Inactive Organization
National Cancer InstituteNational Cancer InstituteCalando Pharmaceuticals, Inc.Calando Pharmaceuticals, Inc.
License Organization-
Drug Highest PhaseDiscontinuedDiscovery
First Approval Date-
Regulation-

Structure/Sequence

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Related

100 Clinical Results associated with Anti-HIF-2alpha siRNA therapy (Calando)
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100 Translational Medicine associated with Anti-HIF-2alpha siRNA therapy (Calando)
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100 Patents (Medical) associated with Anti-HIF-2alpha siRNA therapy (Calando)
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100 Deals associated with Anti-HIF-2alpha siRNA therapy (Calando)
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Solid tumorDiscovery
United States
Calando Pharmaceuticals, Inc.Calando Pharmaceuticals, Inc.
15 Sep 2008
NeuroblastomaDiscovery
United States
National Cancer InstituteNational Cancer Institute
03 Feb 2006
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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