Last update 07 Nov 2024

Eflornithine Hydrochloride Hydrate/Sulindac

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
CPP-1X/sulindac, CPP1-x/sulindac, Eflornithine/sulindac
+ [2]
Target
Mechanism
COX inhibitors(Cyclooxygenases inhibitors), ODC inhibitors(Ornithine decarboxylase inhibitors)
Active Indication-
Inactive Indication
Active Organization-
Drug Highest PhaseDiscontinuedNDA/BLA
First Approval Date-
RegulationOrphan Drug (US), Fast Track (US), Orphan Drug (EU)
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Structure

Molecular FormulaC6H15ClF2N2O3
InChIKeyFJPAMFNRCFEGSD-UHFFFAOYSA-N
CAS Registry96020-91-6
View All Structures (2)

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Adenomatous Polyposis ColiNDA/BLA
EU
10 Jul 2020
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
171
(Eflornithine Plus Sulindac)
cysdlnjcaz(hddesdszlh) = xppxkkavfw ibnaicvjjx (cjgxgyykbh, exbduduqoy - gmckxdldch)
-
08 Jun 2021
Sulindac placebo+Eflornithine
(Eflornithine Plus Sulindac Placebo)
cysdlnjcaz(hddesdszlh) = mkjqxurhra ibnaicvjjx (cjgxgyykbh, xruvmddpki - vncuhyuymt)
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Clinical Trial

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Approval

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Regulation

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