Last update 25 Oct 2025

Chlorpheniramine Maleate/Hydrocodone Bitartrate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Chlorpheniramine/hydrocodone, Hydrocodone bitartrate/Chlorphenamine maleate, Hydrocodone/chlorpheniramine
+ [1]
Target
H1 receptor x Opioid receptors
Action
antagonists, agonists
Mechanism
H1 receptor antagonists(Histamine H1 receptor antagonists), Opioid receptors agonists(Opioid receptors agonists)
Therapeutic Areas
Immune System DiseasesInfectious DiseasesOtorhinolaryngologic Diseases+ [1]
Active Indication-
Inactive Indication
Common ColdCoughRespiratory Hypersensitivity+ [1]
Originator Organization
Cypress Pharmaceuticals, Inc.Cypress Pharmaceuticals, Inc.
Active Organization-
Inactive Organization
Persion Pharmaceuticals LLCPersion Pharmaceuticals LLC
License Organization-
Drug Highest PhaseWithdrawn
First Approval Date
United States (20 Feb 2013),
Common ColdCoughRespiratory Hypersensitivity+ [1]
Regulation-
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Structure/Sequence

Molecular FormulaC20H23ClN2O4
InChIKeyDBAKFASWICGISY-BTJKTKAUSA-N
CAS Registry113-92-8
View All Structures (2)

Related

100 Clinical Results associated with Chlorpheniramine Maleate/Hydrocodone Bitartrate
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100 Translational Medicine associated with Chlorpheniramine Maleate/Hydrocodone Bitartrate
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100 Patents (Medical) associated with Chlorpheniramine Maleate/Hydrocodone Bitartrate
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100 Deals associated with Chlorpheniramine Maleate/Hydrocodone Bitartrate
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External Link

KEGGWikiATCDrug Bank
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R06AB54
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R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Common Cold
United States
Persion Pharmaceuticals LLCPersion Pharmaceuticals LLC
20 Feb 2013
Cough
United States
Persion Pharmaceuticals LLCPersion Pharmaceuticals LLC
20 Feb 2013
Respiratory Hypersensitivity
United States
Persion Pharmaceuticals LLCPersion Pharmaceuticals LLC
20 Feb 2013
Upper respiratory tract allergy
United States
Persion Pharmaceuticals LLCPersion Pharmaceuticals LLC
20 Feb 2013
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Clinical Result

Indication
Phase
Evaluation
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Phase
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Approval

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Regulation

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