Last update 14 Jun 2025

VX-973

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
VX 973, VX973
Target
Nav1.8
Action
blockers
Mechanism
Nav1.8 blockers(Sodium channel protein type X alpha subunit blockers)
Therapeutic Areas
Nervous System DiseasesOther Diseases
Active Indication
Pain
Inactive Indication-
Originator Organization
Vertex Pharmaceuticals, Inc.Vertex Pharmaceuticals, Inc.
Active Organization
Vertex Pharmaceuticals, Inc.Vertex Pharmaceuticals, Inc.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with VX-973
NCT06615570
/ RecruitingPhase 1
A Phase 1, Randomized, Double-blind, Placebo-controlled, Single- and Multiple-dose Escalation Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics of VX-973 in Healthy Adults
NCT05866055
/ CompletedPhase 1
A Phase 1, Randomized, Double-blind, Placebo-controlled, Single- and Multiple-dose Escalation Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics of VX-973 in Healthy Adults
100 Clinical Results associated with VX-973
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100 Translational Medicine associated with VX-973
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100 Patents (Medical) associated with VX-973
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100 Deals associated with VX-973
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
PainPhase 1
United Kingdom
Vertex Pharmaceuticals, Inc.Vertex Pharmaceuticals, Inc.
10 May 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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