Last update 21 Nov 2024

CLL-442

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Target
PI3Kα x mTOR
Mechanism
PI3Kα inhibitors(Phosphatidylinositol 3 kinase alpha inhibitors), mTOR inhibitors(Serine/threonine-protein kinase mTOR inhibitors)
Therapeutic Areas
Neoplasms
Active Indication
Squamous Cell Carcinoma
Inactive Indication
Cutaneous Squamous Cell Carcinoma
Originator Organization
Novartis Pharma AG
Active Organization
Novartis Pharma AG
Inactive Organization
Novartis Pharmaceuticals Corp.Novartis Pharmaceuticals Corp.
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with CLL-442
EUCTR2017-003495-31-BE / Not yet recruitingPhase 1/2
A randomized, Investigator-and patient-blind, placebo-controlled, parallel group first in human and proof of concept study to evaluate the safety, tolerability, and efficacy of CLL442 in patients with Cutaneous Squamous Cell Carcinoma in situ (SCCis) - Not applicable
100 Clinical Results associated with CLL-442
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100 Translational Medicine associated with CLL-442
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100 Patents (Medical) associated with CLL-442
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100 Deals associated with CLL-442
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Squamous Cell CarcinomaPhase 2-
Novartis Pharma AG
-
Cutaneous Squamous Cell CarcinomaDiscovery
US
Novartis Pharmaceuticals Corp.Novartis Pharmaceuticals Corp.
14 Dec 2017
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Clinical Result

Indication
Phase
Evaluation
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Phase
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Clinical Trial

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Approval

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Regulation

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