Effects of Imidacloprid Applied Alone or in Combination With Organosilicone Surfactants on Biological Traits and Predatory Feeding ofChrysoperla nipponensis(Neuroptera: Chrysopidae)

Q2 · AGRICULTURAL & FORESTRY SCIENCE

Article

Author: Fan, Jianbin ; Yang, Jing ; Zhang, Pengjiu ; Fan, Renjun ; Gao, Yue ; Liu, Zhongfang

AbstractOrganosilicone adjuvants are widely used to increase insecticide application on targeted surfaces. In this work, our aim was to investigate side effects of imidacloprid treatment, either applied alone or in combination with organosilicone compounds, against Chrysoperla nipponensis, an important predator of aphids. Four types of organosilicones were mixed with imidacloprid at different concentrations. The toxicity of the mixture to C. nipponensis was measured under laboratory conditions. The LC50 and LC30 of imidacloprid applied alone and in combination with 0.05% organosilicone were determined. Imidacloprid (LC30) applied alone or in combination with 0.05% organosilicone was used to treat second instar larvae of C. nipponensis; thereafter, its effects on the growth, development, longevity, reproduction, and predatory ability of C. nipponensis were evaluated The results demonstrated that the organosilicone Silwet L-77 reduced the LC50 and LC30 of imidacloprid to 6.09 (95% CI: 2.31–9.42) and 10.95 mg/L (95% CI: 8.16–13.63), respectively, and enhanced imidacloprid toxicity to C. nipponensis, as reflected by the resulting extension of the growth and developmental period, reduction in female longevity, and inhibition of reproduction. When applied alone or in combination with an organosilicone, imidacloprid reduced the consumption of Corcyra cephalonica eggs by C. nipponensis. The functional response of C. nipponensis treated with imidacloprid alone or in combination with organosilicone was type II. Concomitantly, the attack rate was reduced and the handling time of prey increased.

01 May 2020·Phytopathology®Q2 · AGRICULTURAL & FORESTRY SCIENCE

Discovery and Characterization of Low-Molecular Weight Inhibitors of Erwinia tracheiphila

Q2 · AGRICULTURAL & FORESTRY SCIENCE

Article

Author: Miller, Sally A. ; Vrisman, Cláudio M. ; Rajashekara, Gireesh ; Johnson, Reed ; Helmy, Yosra A. ; Deblais, Loïc

Plant pathogenic bacteria in the genus Erwinia cause economically important diseases, including bacterial wilt of cucurbits caused by Erwinia tracheiphila. Conventional bactericides are insufficient to control this disease. Using high-throughput screening, 464 small molecules (SMs) with either cidal or static activity at 100 µM against a cucumber strain of E. tracheiphila were identified. Among them, 20 SMs (SM1 to SM20), composed of nine distinct chemical moiety structures, were cidal to multiple E. tracheiphila strains at 100 µM. These lead SMs had low toxicity to human cells and honey bees at 100 µM. No phytotoxicity was observed on melon plants at 100 µM, except when SM12 was either mixed with Silwet L-77 and foliar sprayed or when delivered through the roots. Lead SMs did not inhibit the growth of beneficial Pseudomonas and Enterobacter species but inhibited the growth of Bacillus species. Nineteen SMs were cidal to Xanthomonas cucurbitae and showed >50% growth inhibition against Pseudomonas syringae pv. lachrymans. In addition, 19 SMs were cidal or static against Erwinia amylovora in vitro. Five SMs demonstrated potential to suppress E. tracheiphila when foliar sprayed on melon plants at 2× the minimum bactericidal concentration. Thirteen SMs reduced Et load in melon plants when delivered via roots. Temperature and light did not affect the activity of SMs. In vitro cidal activity was observed after 3 to 10 h of exposure to these five SMs. Here, we report 19 SMs that provide chemical scaffolds for future development of bactericides against plant pathogenic bacterial species.

01 Feb 2003·Journal of Economic EntomologyQ2 · AGRICULTURAL & FORESTRY SCIENCE

Efficacy of Silwet L-77 Against Several Arthropod Pests of Table Grape

Q2 · AGRICULTURAL & FORESTRY SCIENCE

Article

Author: Elizabeth J. Mitcham ; Veronique Bikoba ; Christopher Tipping ; Gabriel J. Chander

Silwet L-77, an organosilicone surfactant, was applied to several arthropod pests of California table grapes. Eggs of grape mealybug, Pseudococcus maritimus (Ehrhorn), and omnivorous leafroller, Platynota stultana Walsingham, were tolerant to 0.1, 0.25, and 0.5% treatment solutions; however, eggs of Pacific spider mite, Tetranychus pacificus McGregor, were highly susceptible with mortality >99.4% (0.1% Silwet L-77). Mortality of immature and adult stages of cotton aphid (Aphis gossypii Glover), Western flower thrips (Frankliniella occidentalis Pergande), and Pacific spider mite (Tetranychus pacificus McGregor) was > or = 93.8, > or = 98.5, and > or = 99.4% for 0.1, 0.25, and 0.5% Silwet L-77, respectively. Grape mealybug crawlers had 100% mortality when treated with 0.5 and 1.0% Silwet L-77 solutions; however, mortality was only 6.7% when 0.1% Silwet L-77 was applied. 'Thompson Seedless' table grapes were not damaged when treated with up to 1% Silwet L-77; however, grapes treated with the 0.5 and 1.0% solutions appeared wet after removal from cold storage because of the effect of the surfactant spreading the water condensation. Grapes dried with the normal bloom on the berries when they reached room temperature.

100 Deals associated with CE-1037

R&D Status

10 top R&D records.

to view more data

Indication	Highest Phase	Country/Location	Organization	Date
Cystic Fibrosis	Phase 2	-	United Therapeutics Corp.	-
Cystic Fibrosis	Phase 2	US	-	-
Cystic Fibrosis	Phase 2	-	Cortech, Inc.	-
Pulmonary Disease, Chronic Obstructive	Phase 2	-	Cortech, Inc.	-
Pulmonary Disease, Chronic Obstructive	Phase 2	-	United Therapeutics Corp.	-
Pulmonary Disease, Chronic Obstructive	Phase 2	US	-	-
Pulmonary Emphysema	Phase 2	US	-	-
Respiratory Distress Syndrome, Adult	Phase 2	-	United Therapeutics Corp.	-
Respiratory Distress Syndrome, Adult	Phase 2	-	Cortech, Inc.	-
Respiratory Distress Syndrome, Adult	Phase 2	US	-	-

Clinical Result

Indication

Phase

Evaluation

View All Results

Translational Medicine

Boost your research with our translational medicine data.

view full example data

Deal

Boost your decision using our deal data.

view full example data

Core Patent

Boost your research with our Core Patent data.

view full example data

Clinical Trial

Identify the latest clinical trials across global registries.

view full example data

Approval

Accelerate your research with the latest regulatory approval information.

view full example data

Regulation

Understand key drug designations in just a few clicks with Synapse.

view full example data

Chat with Hiro

Get started for free today!

Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.

Start your data trial now!

Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.

Bio

Bio Sequences Search & Analysis

Chemical

Chemical Structures Search & Analysis


No Data

CE-1037

Overview

Basic Info

Structure

Related

R&D Status

Clinical Result

Translational Medicine

Deal

Core Patent

Clinical Trial

Approval

Regulation