[Translation] A single-center, randomized, open-label, four-period, repeated crossover, single-dose comparative study of the pharmacokinetics, pharmacodynamics, and safety of human glucagon for injection versus Novazoma® for subcutaneous injection in healthy Chinese subjects
主要目的
1.评价与对照组诺和生®相比,受试者单次皮下注射注射用人高血糖素后,高血糖素药代动力学较基线的变化。
次要目的
1.评价与对照组诺和生®相比,受试者单次皮下注射注射用人高血糖素后,高血糖素药效动力学较基线的变化。
2.评价与阳性对照组诺和生®相比,单次皮下注射注射用人高血糖素在中国健康受试者中的安全性。
[Translation] Main purpose
1. To evaluate the changes in the pharmacokinetics of glucagon compared with baseline after a single subcutaneous injection of human glucagon in subjects compared with the control group, Novosun®.
Secondary purpose
1. To evaluate the changes in the pharmacodynamics of glucagon compared with baseline after a single subcutaneous injection of human glucagon in subjects compared with the control group, Novosun®.
2. To evaluate the safety of a single subcutaneous injection of human glucagon in Chinese healthy subjects compared with the positive control group, Novosun®.