Last update 21 Nov 2024

BL-1021

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Target
Nav1.6 x Nav1.7 x Nav1.8
Mechanism
Nav1.6 blockers(Sodium channel protein type VIII alpha subunit blockers), Nav1.7 blockers(Sodium channel protein type IX alpha subunit blockers), Nav1.8 blockers(Sodium channel protein type X alpha subunit blockers)
Therapeutic Areas
Nervous System Diseases
Active Indication-
Inactive Indication
Neuralgia
Originator Organization
Bar-Ilan UniversityBar-Ilan University
Active Organization-
Inactive Organization
Bar-Ilan UniversityBar-Ilan UniversityBioLineRx Ltd.BioLineRx Ltd.Ramot at Tel Aviv University Ltd.Ramot at Tel Aviv University Ltd.
Drug Highest PhaseDiscontinuedPhase 1
First Approval Date-
Regulation-
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Structure

Molecular FormulaC23H28N2O
InChIKeyDOIAVGICIXNFIH-UHFFFAOYSA-N
CAS Registry1002404-34-3
View All Structures (2)

Related

1
Clinical Trials associated with BL-1021
NCT01121380 / TerminatedPhase 1
A First-in-Human, Randomized, Double-Blind, Placebo Controlled, Single-Center Combined Single-Ascending Dose and Multiple-Ascending Dose, Parallel Groups, Study to Assess Safety, Tolerability and Pharmacokinetics of BL-1021 in Healthy Volunteers
100 Clinical Results associated with BL-1021
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100 Translational Medicine associated with BL-1021
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100 Patents (Medical) associated with BL-1021
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100 Deals associated with BL-1021
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
NeuralgiaPhase 1-
Bar-Ilan UniversityBar-Ilan University
-
NeuralgiaPhase 1-
Ramot at Tel Aviv University Ltd.Ramot at Tel Aviv University Ltd.
-
NeuralgiaPhase 1-
Bar-Ilan UniversityBar-Ilan University
-
NeuralgiaPhase 1-
Ramot at Tel Aviv University Ltd.Ramot at Tel Aviv University Ltd.
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Approval

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Regulation

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