Last update 29 Nov 2025

KTN-0125

Overview

Basic Info

Drug Type
Antibody drug conjugate (ADC)
Synonyms
CDX-0125-TEI, KTN-0125
Target
ALK
Action
inhibitors
Mechanism
ALK inhibitors(Anaplastic lymphoma kinase inhibitors)
Therapeutic Areas
NeoplasmsOther Diseases
Active Indication-
Inactive Indication
Neuroblastoma
Originator Organization
Kolltan Pharmaceuticals, Inc.Kolltan Pharmaceuticals, Inc.
Active Organization-
Inactive Organization
Children's HospitalNerviano Medical Sciences S.r.lCelldex Therapeutics, Inc.Celldex Therapeutics, Inc.
License Organization-
Drug Highest PhasePendingPreclinical
First Approval Date-
Regulation-

Structure/Sequence

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Related

100 Clinical Results associated with KTN-0125
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100 Translational Medicine associated with KTN-0125
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100 Patents (Medical) associated with KTN-0125
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100 Deals associated with KTN-0125
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
NeuroblastomaPreclinical
United States
Celldex Therapeutics, Inc.Celldex Therapeutics, Inc.
13 Mar 2019
NeuroblastomaPreclinical
United States
Children's Hospital
13 Mar 2019
NeuroblastomaPreclinical
Italy
Nerviano Medical Sciences S.r.l
13 Mar 2019
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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