Last update 05 Apr 2025

NDI-219216

Overview

Basic Info

Drug Type
Chemical drugs
Synonyms
NDI 219216, NDI219216
Target
WRN
Action
inhibitors
Mechanism
WRN inhibitors(WRN RecQ like helicase inhibitors)
Therapeutic Areas
NeoplasmsNervous System DiseasesCongenital Disorders+ [1]
Active Indication
Advanced Malignant Solid NeoplasmMicrosatellite instability-high cancerTurcot Syndrome
Inactive Indication-
Originator Organization
Nimbus Therapeutics LLCNimbus Therapeutics LLC
Active Organization
Nimbus Therapeutics LLCNimbus Therapeutics LLC
Inactive Organization-
Drug Highest PhasePhase 1/2
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with NDI-219216
NCT06898450
/ RecruitingPhase 1/2
A Phase 1/2 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of NDI-219216 in Patients With Advanced Solid Tumors With/Without Microsatellite Instability and/or Deficient Mismatch Repair
100 Clinical Results associated with NDI-219216
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100 Translational Medicine associated with NDI-219216
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100 Patents (Medical) associated with NDI-219216
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100 Deals associated with NDI-219216
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 2
United States
Nimbus Therapeutics LLCNimbus Therapeutics LLC
31 Mar 2025
Microsatellite instability-high cancerPhase 2
United States
Nimbus Therapeutics LLCNimbus Therapeutics LLC
31 Mar 2025
Turcot SyndromePhase 2
United States
Nimbus Therapeutics LLCNimbus Therapeutics LLC
31 Mar 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Clinical Trial

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Approval

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Regulation

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