Delving into the Latest Updates on ALXN2080 with Synapse

Overview

Basic Info

Drug Type

Small molecule drug

Synonyms

Target

CFD

Action

inhibitors

Mechanism

CFD inhibitors(Complement factor D inhibitors)

Therapeutic Areas-

Active Indication-

Inactive Indication-

Originator Organization

Alexion Pharmaceuticals, Inc.

Active Organization

Alexion Pharmaceuticals, Inc.

Inactive Organization-

License Organization-

Drug Highest PhasePhase 1

First Approval Date-

Regulation-

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The primary objectives of this study are to determine the effect of multiple doses of itraconazole on the single dose PK of ALXN2080, to determine the effect of multiple doses of fluconazole on the single dose PK of ALXN2080 (optional), and to determine the effect of multiple doses of carbamazepine on the single dose PK of ALXN2080.

Start Date10 Jan 2024

Sponsor / Collaborator

Alexion Pharmaceuticals, Inc.

NCT06160414

/ CompletedPhase 1

A Phase 1 Study to Evaluate the Potential Drug Interactions Between ALXN2080 and Rosuvastatin and Metformin in Healthy Adult Participants

The primary objectives of this study are to determine the effect of multiple doses of ALXN2080 on the single-dose PK of rosuvastatin and to determine the effect of multiple doses of ALXN2080 on the single-dose PK of metformin.

Start Date12 Apr 2023

Sponsor / Collaborator

Alexion Pharmaceuticals, Inc.

NCT05428696

/ CompletedPhase 1

A Randomized, Double-blind, Placebo-controlled First-in-Human Study of Single and Multiple Doses of ALXN2080 in Healthy Participants

This study is designed to evaluate the safety and tolerability, pharmacokinetics and pharmacodynamics of single and multiple doses of ALXN2080 in healthy adult participants.

Start Date12 Sep 2022

Sponsor / Collaborator

Alexion Pharmaceuticals, Inc.

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100 Clinical Results associated with ALXN2080

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100 Translational Medicine associated with ALXN2080

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100 Patents (Medical) associated with ALXN2080

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100 Deals associated with ALXN2080

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