The aim of this study was to evaluate the effects of electret and Ligusticum wallichii (Chuangxiong, a traditional Chinese herb medicine) on the functional recovery of muscle grafts. Twenty-eight adult dogs were divided into 4 groups with each consisting of 7 animals. After orthotopical transplantation of bilateral rectus femoris muscle with neurovascular anastomosis, group A received electret local implant, group B received Chuangxiong injection, group C received both electret local implant and Chuangxiong injection and group D was used as control. The results showed that the functional recovery of the transplanted rectus femoris muscle in group A and B was better than group D while group C was the best. At 22 postoperative weeks, the recovery rate of maximal tetanic tension was 64.94 +/- 3.82% in group c: 57.68 +/- 1.67% in group A, 53.64 +/- 3.82% in group B and 47.99 +/- 2.21% in group D (P < 0.05). The structural recovery of the transplanted muscle in group C was closest to the normal.