Last update 21 Apr 2026

RGT-490

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms-
Target
PI3Kα
Action
inhibitors
Mechanism
PI3Kα inhibitors(Phosphatidylinositol 3 kinase alpha inhibitors)
Therapeutic Areas-
Active Indication-
Inactive Indication-
Originator Organization
Shanghai Qilu Ruige Pharmaceutical R&D Co., Ltd.Shanghai Qilu Ruige Pharmaceutical R&D Co., Ltd.
Active Organization
Regor Therapeutics GroupRegor Therapeutics Group
Shanghai Qilu Ruige Pharmaceutical R&D Co., Ltd.Shanghai Qilu Ruige Pharmaceutical R&D Co., Ltd.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with RGT-490
NCT07524322
/ RecruitingPhase 1
A Phase 1/1b Open-Label, Multicenter, First-in-Human Study Evaluating Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of RGT-490 as a Single Agent in Adult Subjects With Locally Advanced or Metastatic PIK3CA-Mutated Solid Tumors Including HR+/HER2- Breast Cancers
100 Clinical Results associated with RGT-490
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100 Translational Medicine associated with RGT-490
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100 Patents (Medical) associated with RGT-490
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100 Deals associated with RGT-490
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R&D Status

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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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