Last update 24 May 2025

BMS-986406

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
BMS 986406, BMS-986406, BMS986406
Target
LILRB2
Action
inhibitors
Mechanism
LILRB2 inhibitors(Leukocyte immunoglobulin-like receptor subfamily B member 2 inhibitors)
Therapeutic Areas
Neoplasms
Active Indication
Locally Advanced Malignant Neoplasm
Inactive Indication-
Originator Organization
Bristol-Myers Squibb Pharmaceuticals Ltd.
Active Organization
Bristol Myers Squibb Co.Bristol Myers Squibb Co.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with BMS-986406
CTIS2023-508280-69-00
/ Not yet recruitingPhase 1
- CA111-001
NCT05298592
/ CompletedPhase 1
A Phase 1 First-in-human Study of BMS-986406 as Monotherapy and Combination Therapies in Participants With Advanced Malignant Tumors
100 Clinical Results associated with BMS-986406
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100 Translational Medicine associated with BMS-986406
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100 Patents (Medical) associated with BMS-986406
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100 Deals associated with BMS-986406
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Locally Advanced Malignant NeoplasmPhase 1
United States
Bristol Myers Squibb Co.Bristol Myers Squibb Co.
31 Mar 2022
Locally Advanced Malignant NeoplasmPhase 1
Japan
Bristol Myers Squibb Co.Bristol Myers Squibb Co.
31 Mar 2022
Locally Advanced Malignant NeoplasmPhase 1
Argentina
Bristol Myers Squibb Co.Bristol Myers Squibb Co.
31 Mar 2022
Locally Advanced Malignant NeoplasmPhase 1
Belgium
Bristol Myers Squibb Co.Bristol Myers Squibb Co.
31 Mar 2022
Locally Advanced Malignant NeoplasmPhase 1
Spain
Bristol Myers Squibb Co.Bristol Myers Squibb Co.
31 Mar 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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