Last update 08 May 2025

RN-1(University of Michigan)

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms-
Target
KDM1A x SEC23A
Action
inhibitors
Mechanism
KDM1A inhibitors(Lysine-specific histone demethylase 1 inhibitors), SEC23A inhibitors(SEC23 homolog A, COPII coat complex component inhibitors)
Therapeutic Areas
Congenital DisordersHemic and Lymphatic DiseasesOther Diseases
Active Indication
Anemia, Dyserythropoietic, CongenitalAnemia, Sickle Cell
Inactive Indication-
Originator Organization
University of MichiganUniversity of Michigan
Active Organization
University of MichiganUniversity of Michigan
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with RN-1(University of Michigan)
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100 Translational Medicine associated with RN-1(University of Michigan)
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100 Patents (Medical) associated with RN-1(University of Michigan)
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1
Literatures (Medical) associated with RN-1(University of Michigan)
16 Jul 2015BloodQ1 · MEDICINE
The LSD1 inhibitor RN-1 induces fetal hemoglobin synthesis and reduces disease pathology in sickle cell mice
Q1 · MEDICINE
100 Deals associated with RN-1(University of Michigan)
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Anemia, Dyserythropoietic, CongenitalPreclinical
United States
University of MichiganUniversity of Michigan
09 Dec 2024
Anemia, Sickle CellPreclinical
United States
University of MichiganUniversity of Michigan
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Translational Medicine

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Deal

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Clinical Trial

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Approval

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Regulation

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