Last update 20 Jun 2025

MAGE-C2/HLA-A2 TCR T cells(Erasmus Medical Center)

Overview

Basic Info

Drug Type
TCR-T Cell therapy
Synonyms
Adoptive therapy with autologous MC2 TCR T cells, MC2 TCR T cells
Target-
Action-
Mechanism-
Therapeutic Areas
NeoplasmsEye DiseasesSkin and Musculoskeletal Diseases+ [1]
Active Indication
Squamous Cell Carcinoma of Head and NeckUveal Melanoma
Inactive Indication-
Originator Organization
Erasmus MC
Active Organization
Erasmus MC
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1/2
First Approval Date-
Regulation-

Related

1
Clinical Trials associated with MAGE-C2/HLA-A2 TCR T cells(Erasmus Medical Center)
NCT04729543
/ RecruitingPhase 1/2IIT
Adoptive Therapy With TCR Gene-engineered T Cells to Treat Patients With MAGE-C2-positive Melanoma and Head and Neck Cancer
100 Clinical Results associated with MAGE-C2/HLA-A2 TCR T cells(Erasmus Medical Center)
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100 Translational Medicine associated with MAGE-C2/HLA-A2 TCR T cells(Erasmus Medical Center)
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100 Patents (Medical) associated with MAGE-C2/HLA-A2 TCR T cells(Erasmus Medical Center)
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100 Deals associated with MAGE-C2/HLA-A2 TCR T cells(Erasmus Medical Center)
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Squamous Cell Carcinoma of Head and NeckPhase 2
Netherlands
Erasmus MC
20 Oct 2020
Uveal MelanomaPhase 2
Netherlands
Erasmus MC
20 Oct 2020
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Clinical Result

Indication
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Clinical Trial

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Approval

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Regulation

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