Last update 30 Aug 2025

FHT-185

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
FHT 185, FHT185
Target
SMARCA2 x SMARCA4
Action
inhibitors
Mechanism
SMARCA2 inhibitors(Probable global transcription activator SNF2L2 inhibitors), SMARCA4 inhibitors(Transcription activator BRG1 inhibitors)
Therapeutic Areas
Neoplasms
Active Indication-
Inactive Indication
Neoplasms
Originator Organization
Foghorn Therapeutics, Inc.Foghorn Therapeutics, Inc.
Active Organization-
Inactive Organization
Foghorn Therapeutics, Inc.Foghorn Therapeutics, Inc.
License Organization-
Drug Highest PhasePendingDiscovery
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC20H20N4O4S2
InChIKeyFNJDMRMVWHPFCX-UHFFFAOYSA-N
CAS Registry878254-76-3

Related

100 Clinical Results associated with FHT-185
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100 Translational Medicine associated with FHT-185
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100 Patents (Medical) associated with FHT-185
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100 Deals associated with FHT-185
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
NeoplasmsDiscovery
United States
Foghorn Therapeutics, Inc.Foghorn Therapeutics, Inc.
30 Apr 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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