Last update 06 Dec 2025

STING degrader 2h (SIMM)

Overview

Basic Info

Drug Type
Proteolysis-targeting chimeras (PROTAC)
Synonyms-
Target
STING
Action
degraders
Mechanism
STING degraders(Stimulator of interferon genes degraders)
Therapeutic Areas
Immune System DiseasesOther Diseases
Active Indication
Autoimmune DiseasesInflammation
Inactive Indication-
Originator Organization
University of Chinese Academy of SciencesUniversity of Chinese Academy of SciencesShanghai Institute of Materia Medica Chinese Academy of SciShanghai Institute of Materia Medica Chinese Academy of Sci
Active Organization
Shanghai Institute of Materia Medica Chinese Academy of SciShanghai Institute of Materia Medica Chinese Academy of SciUniversity of Chinese Academy of SciencesUniversity of Chinese Academy of Sciences
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC39H42Cl2N8O9
InChIKeyFGTYORLXIPLJJD-UHFFFAOYSA-N
CAS Registry3098871-32-7

Related

100 Clinical Results associated with STING degrader 2h (SIMM)
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100 Translational Medicine associated with STING degrader 2h (SIMM)
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100 Patents (Medical) associated with STING degrader 2h (SIMM)
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100 Deals associated with STING degrader 2h (SIMM)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Autoimmune DiseasesPreclinical
China
Shanghai Institute of Materia Medica Chinese Academy of SciShanghai Institute of Materia Medica Chinese Academy of Sci
12 May 2025
Autoimmune DiseasesPreclinical
China
University of Chinese Academy of SciencesUniversity of Chinese Academy of Sciences
12 May 2025
InflammationPreclinical
China
University of Chinese Academy of SciencesUniversity of Chinese Academy of Sciences
12 May 2025
InflammationPreclinical
China
Shanghai Institute of Materia Medica Chinese Academy of SciShanghai Institute of Materia Medica Chinese Academy of Sci
12 May 2025
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Clinical Result

Indication
Phase
Evaluation
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Phase
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Deal

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Clinical Trial

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Approval

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Regulation

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