GEN-1078

The purpose of this trial is to measure the following in participants with solid cancers who receive GEN1078.
* The side effects seen with GEN1078
* What the body does with GEN1078 once it is administered
* What GEN1078 does to the body once it is administered
* How well GEN1078 works against advanced solid tumors
Trial details include:
* The estimated trial duration is 8 months for an individual participant (the trial duration may vary for each participant).
* The treatment duration will be an estimated 3-month treatment period (the duration of treatment may vary for each participant).
* The visit frequency will be daily or visits every few days for the first few months.
All participants will receive active drug; no one will be given placebo.