Last update 21 Feb 2026

SHP-389

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
SHP-389
Target
SHP2
Action
inhibitors
Mechanism
SHP2 inhibitors(Src homology phosphotyrosyl phosphatase 2 inhibitors)
Therapeutic Areas
Neoplasms
Active Indication-
Inactive Indication
Neoplasms
Originator Organization
Novartis Pharmaceuticals Corp.Novartis Pharmaceuticals Corp.Novartis Institutes for Biomedical Research, Inc.Novartis Institutes for Biomedical Research, Inc.
Active Organization-
Inactive Organization
Novartis Institutes for Biomedical Research, Inc.Novartis Institutes for Biomedical Research, Inc.Novartis Pharmaceuticals Corp.Novartis Pharmaceuticals Corp.
License Organization-
Drug Highest PhasePendingPreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC23H29ClN8O2
InChIKeyURUPFUYPXLMTMT-KPZWWZAWSA-N
CAS Registry2055938-05-9

Related

100 Clinical Results associated with SHP-389
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100 Translational Medicine associated with SHP-389
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100 Patents (Medical) associated with SHP-389
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100 Deals associated with SHP-389
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
NeoplasmsPreclinical
United States
Novartis Institutes for Biomedical Research, Inc.Novartis Institutes for Biomedical Research, Inc.
28 Jan 2019
NeoplasmsPreclinical
United States
Novartis Pharmaceuticals Corp.Novartis Pharmaceuticals Corp.
28 Jan 2019
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Clinical Trial

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Approval

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Regulation

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