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Last update 08 Nov 2025
SGB-3403
Last update 08 Nov 2025
Overview
Basic Info
Drug Type siRNA |
Synonyms SGB 3403 |
Target |
Action inhibitors |
Mechanism PCSK9 inhibitors(Proprotein convertase subtilisin kexin type 9 inhibitors) |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhasePhase 1 |
First Approval Date- |
Regulation- |
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Structure/Sequence
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Related
2
Clinical Trials associated with SGB-3403CTR20240125
评价 SGB-3403 注射液在健康受试者及低密度脂蛋白胆固醇（LDL-C）升高受试者中的安全性、耐受性、药代动力学特征以及药效学特征的 I 期临床试验
[Translation] A Phase I clinical trial to evaluate the safety, tolerability, pharmacokinetic characteristics, and pharmacodynamic characteristics of SGB-3403 injection in healthy subjects and subjects with elevated low-density lipoprotein cholesterol (LDL-C)
NCT06239714
A Phase 1, Randomized, Double-Blind, Placebo-Controlled, SAD and MAD Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneously Administered SGB-3403 in Healthy Volunteers and Subjects With Elevated LDL-C
100 Clinical Results associated with SGB-3403
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100 Translational Medicine associated with SGB-3403
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100 Patents (Medical) associated with SGB-3403
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100 Deals associated with SGB-3403
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Atherosclerosis | Phase 1 | China | 20 Feb 2024 | |
| Heterozygous familial hypercholesterolemia | Phase 1 | China | 20 Feb 2024 | |
| Hyperlipidemias | Phase 1 | - | 18 Feb 2024 | |
| Hypercholesterolemia | Phase 1 | Australia | 31 May 2023 | |
| Atherosclerotic occlusive disease | IND Approval | China | 07 Oct 2023 |
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