[Translation] A Phase I clinical study to evaluate the safety, tolerability and pharmacokinetic characteristics of multiple dose escalation of VV119 capsules in Chinese healthy adult subjects and patients with schizophrenia
主要目的:评估中国成年受试者多次口服VV119胶囊的安全性和耐受性;
次要目的:1、评估中国成年受试者多次口服VV119胶囊后原形药物及其主要代谢产物的药代动力学(PK)特征;2、评估VV119胶囊在中国成年精神分裂症患者中的初步疗效。
[Translation] Primary purpose: To evaluate the safety and tolerability of multiple oral administration of VV119 capsules in Chinese adult subjects;
Secondary purpose: 1. To evaluate the pharmacokinetic (PK) characteristics of the parent drug and its main metabolites after multiple oral administration of VV119 capsules in Chinese adult subjects; 2. To evaluate the preliminary efficacy of VV119 capsules in Chinese adult patients with schizophrenia.