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Clinical Trials associated with Rituximab biosimilar(Hualan Genetic Engineering Co Ltd)比较HL03/WBP263与利妥昔单抗联合CHOP化疗药治疗初治弥漫性大B细胞淋巴瘤有效性和安全性的III期临床研究
[Translation] Phase III clinical study comparing the efficacy and safety of HL03/WBP263 and rituximab combined with CHOP chemotherapy in the treatment of newly diagnosed diffuse large B-cell lymphoma
主要目的:评价HL03/WBP263和美罗华®在初治弥漫性大B细胞淋巴瘤(DLBCL)患者中疗效的相似性。 次要目的:评价HL03/WBP263和美罗华®在初治弥漫性大B细胞淋巴瘤(DLBCL)患者中的安全性、药代动力学特征及免疫原性。
[Translation] Primary objective: To evaluate the similarity of efficacy between HL03/WBP263 and Rituximab® in patients with newly diagnosed diffuse large B-cell lymphoma (DLBCL). Secondary objective: To evaluate the safety, pharmacokinetic characteristics and immunogenicity of HL03/WBP263 and Rituximab® in patients with newly diagnosed diffuse large B-cell lymphoma (DLBCL).
比较CR CD20+B细胞非霍奇金淋巴瘤患者单剂量使用WBP263与利妥昔单抗(美罗华?)的药代动力学相似性
[Translation] Comparison of the pharmacokinetic similarity of single-dose WBP263 and rituximab (Rituxan?) in patients with CR CD20+ B-cell non-Hodgkin's lymphoma
主要目的: 比较 CR CD20+B 细胞非霍奇金淋巴瘤患者单剂量使用WBP263 与美罗华的药代动力学特征相似性; 次要目的:1. 比较 CR CD20+B 细胞非霍奇金淋巴瘤患者单剂量使用 WBP263 与美罗华的药效动力学特征相似性(外周血CD19+B 细胞消耗程度和持续时间); 2. 比较 CR CD20+B 细胞非霍奇金淋巴瘤患者单剂量使用 WBP263 与美罗华的安全性; 3. 比较 CR CD20+B 细胞非霍奇金淋巴瘤患者单剂量使用 WBP263 与美罗华的免疫原性;
[Translation] Primary objective: To compare the similarity of pharmacokinetic characteristics of WBP263 and Rituximab after single-dose administration in patients with CR CD20+B-cell non-Hodgkin's lymphoma. Secondary objectives: 1. To compare the similarity of pharmacodynamic characteristics (degree and duration of peripheral blood CD19+B cell depletion) of WBP263 and Rituximab after single-dose administration in patients with CR CD20+B-cell non-Hodgkin's lymphoma. 2. To compare the safety of WBP263 and Rituximab after single-dose administration in patients with CR CD20+B-cell non-Hodgkin's lymphoma. 3. To compare the immunogenicity of WBP263 and Rituximab after single-dose administration in patients with CR CD20+B-cell non-Hodgkin's lymphoma.
100 Clinical Results associated with Rituximab biosimilar(Hualan Genetic Engineering Co Ltd)
100 Translational Medicine associated with Rituximab biosimilar(Hualan Genetic Engineering Co Ltd)
100 Patents (Medical) associated with Rituximab biosimilar(Hualan Genetic Engineering Co Ltd)
100 Deals associated with Rituximab biosimilar(Hualan Genetic Engineering Co Ltd)