Last update 04 Jul 2025

AMB-303

Overview

Basic Info

Drug Type
Antibody drug conjugate (ADC)
Synonyms
AMB 303, AMB303
Target
ROR1 x Top I
Action
antagonists, inhibitors
Mechanism
ROR1 antagonists(Inactive tyrosine-protein kinase transmembrane receptor ROR1 antagonists), TOP1 inhibitors(DNA topoisomerase I inhibitors)
Therapeutic Areas
NeoplasmsRespiratory DiseasesSkin and Musculoskeletal Diseases
Active Indication
Non-Small Cell Lung CancerTriple Negative Breast CancerSolid tumor
Inactive Indication-
Originator Organization
AimedBio, Inc.AimedBio, Inc.
Active Organization
SK Plasma Co., Ltd.SK Plasma Co., Ltd.Samsung Medical CenterSamsung Medical CenterAimedBio, Inc.AimedBio, Inc.
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Structure/Sequence

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Related

100 Clinical Results associated with AMB-303
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100 Translational Medicine associated with AMB-303
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100 Patents (Medical) associated with AMB-303
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100 Deals associated with AMB-303
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Non-Small Cell Lung CancerPreclinical
South Korea
Samsung Medical CenterSamsung Medical Center
29 Apr 2025
Triple Negative Breast CancerPreclinical
South Korea
Samsung Medical CenterSamsung Medical Center
29 Apr 2025
Solid tumorPreclinical
South Korea
AimedBio, Inc.AimedBio, Inc.
01 Nov 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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