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Last update 05 Sep 2026
177Lu-PSMA-R2
Last update 05 Sep 2026
Overview
Basic Info
Drug Type Peptide Conjugate Radionuclide, Therapeutic radiopharmaceuticals |
Synonyms 177LU-PSMA-SR6, AAA-602 |
Target |
Action modulators |
Mechanism PSMA modulators(Prostate-specific membrane antigen modulators) |
Therapeutic Areas |
Active Indication- |
Originator Organization |
Active Organization- |
Inactive Organization |
License Organization- |
Drug Highest PhaseDiscontinuedPhase 1/2 |
First Approval Date- |
Regulation- |
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Structure/Sequence
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Related
2
Clinical Trials associated with 177Lu-PSMA-R2NCT06881823
NeoPSMA: A Phase I/II, Open-label, Multi-center Study of Neoadjuvant Treatment With [177Lu]Lu-PSMA-R2 (AAA602) and [225Ac]Ac-PSMA-R2 (AAA802) in Adults With Prostate-specific Membrane Antigen (PSMA) Positive High-risk Localized Prostate Cancer (HRLPC) Prior to Radical Prostatectomy and Pelvic Lymph Node Dissection
NCT03490838
A Phase 1/2 Open-label, Multi-center, Dose-escalation Study of Safety, Tolerability, Pharmacokinetics, Dosimetry, and Response to Repeat Dosing of 177Lu-PSMA-R2 Radio-ligand Therapy in Patients With Prostate Specific Membrane Antigen (PSMA) Positive (68Ga-PSMA-R2) Progressive Metastatic Castration-resistant Prostate Cancer, Following Previous Systemic Treatment
100 Clinical Results associated with 177Lu-PSMA-R2
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100 Translational Medicine associated with 177Lu-PSMA-R2
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100 Patents (Medical) associated with 177Lu-PSMA-R2
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100 Deals associated with 177Lu-PSMA-R2
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R&D Status
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| PSMA-Positive Prostatic Cancer | Phase 2 | - | 29 Jun 2026 | |
| Metastatic castration-resistant prostate cancer | Phase 1 | United States | 24 May 2018 | |
| Metastatic castration-resistant prostate cancer | Phase 1 | Spain | 24 May 2018 |
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Core Patent
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Regulation
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