Last update 30 Aug 2025

SJ000988500

Overview

Basic Info

Drug Type
Proteolysis-targeting chimeras (PROTAC)
Synonyms
SJ000988500
Target
JAK2
Action
degraders
Mechanism
JAK2 degraders(Tyrosine-protein kinase JAK2 degraders)
Therapeutic Areas
NeoplasmsImmune System DiseasesSkin and Musculoskeletal Diseases
Active Indication-
Inactive Indication
NeoplasmsRheumatoid Arthritis
Originator Organization
Usona InstituteUsona Institute
Active Organization-
Inactive Organization
Usona InstituteUsona Institute
License Organization-
Drug Highest PhasePendingPreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC38H40N10O5
InChIKeyJKVWQNULVWSWIV-UHFFFAOYSA-N
CAS Registry2595365-45-8

Related

100 Clinical Results associated with SJ000988500
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100 Translational Medicine associated with SJ000988500
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100 Patents (Medical) associated with SJ000988500
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1
Literatures (Medical) associated with SJ000988500
10 Jun 2021ACS medicinal chemistry letters
PROTAC-Mediated Degradation of Janus Kinase as a Therapeutic Strategy for Cancer and Rheumatoid Arthritis
100 Deals associated with SJ000988500
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
NeoplasmsPreclinical
United States
Usona InstituteUsona Institute
10 May 2021
Rheumatoid ArthritisPreclinical
United States
Usona InstituteUsona Institute
10 May 2021
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Clinical Result

Indication
Phase
Evaluation
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Clinical Trial

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Approval

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Regulation

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