Last update 21 Nov 2024

Dapivirine/Maraviroc

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms-
Target
CCR5 x RT
Mechanism
CCR5 antagonists(C-C chemokine receptor type 5 antagonists), RT inhibitors(Reverse transcriptase inhibitors)
Therapeutic Areas
Immune System DiseasesInfectious DiseasesUrogenital Diseases
Active Indication-
Inactive Indication
HIV Infections
Originator Organization
Microbicide Trials NetworkMicrobicide Trials Network
Active Organization-
Inactive Organization
International Partnership for MicrobicidesInternational Partnership for Microbicides
Drug Highest PhasePendingPhase 1
First Approval Date-
Regulation-
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Structure

Molecular FormulaC29H41F2N5O
InChIKeyGSNHKUDZZFZSJB-QYOOZWMWSA-N
CAS Registry376348-65-1
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Related

2
Clinical Trials associated with Dapivirine/Maraviroc
NCT01363037 / CompletedPhase 1
Phase 1 Safety and Pharmacokinetics of Dapivirine/Maraviroc Vaginal Ring
NCT01242579 / WithdrawnPhase 1
A Double-Blind, Randomised, Placebo-Controlled Phase I Trial to Compare the Pharmacokinetics of Maraviroc and Dapivirine Following Application of Maraviroc Vaginal Vaginal Gel, 0.1% 2.5g, Dapivirine Vaginal Gel, 0.05%, 2.5g and Maraviroc 0.1% + Dapivirine 0.05% Vaginal Gel, 2.5g Formulations, and to Assess Their Safety as Compared to the Matching Placebo Vaginal Gel, 2.5g in Healthy, HIV-Negative Women
100 Clinical Results associated with Dapivirine/Maraviroc
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100 Translational Medicine associated with Dapivirine/Maraviroc
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100 Patents (Medical) associated with Dapivirine/Maraviroc
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100 Deals associated with Dapivirine/Maraviroc
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
HIV InfectionsPhase 1
US
International Partnership for MicrobicidesInternational Partnership for Microbicides
01 Nov 2011
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Approval

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Regulation

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