Last update 30 Mar 2025

Pmd-PEG5-3C-Dab#1

Overview

Basic Info

Drug Type
Proteolysis-targeting chimeras (PROTAC)
Synonyms
Pmd-PEG5-3C-Dab#1
Target
BRAF V600E
Action
inhibitors
Mechanism
BRAF V600E inhibitors
Therapeutic Areas
NeoplasmsSkin and Musculoskeletal Diseases
Active Indication-
Inactive Indication
BRAF V600E Mutation-Positive Melanoma
Originator Organization
University of TorontoUniversity of Toronto
Active Organization-
Inactive Organization
Ontario Institute for Cancer ResearchOntario Institute for Cancer ResearchUniversity of TorontoUniversity of TorontoLunenfeld-Tanenbaum Research InstituteLunenfeld-Tanenbaum Research Institute
Drug Highest PhasePendingPreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC52H60F3N9O12S2
InChIKeyVIUIPUTXCBUDAQ-UHFFFAOYSA-N
CAS Registry-

Related

100 Clinical Results associated with Pmd-PEG5-3C-Dab#1
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100 Translational Medicine associated with Pmd-PEG5-3C-Dab#1
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100 Patents (Medical) associated with Pmd-PEG5-3C-Dab#1
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100 Deals associated with Pmd-PEG5-3C-Dab#1
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
BRAF V600E Mutation-Positive MelanomaPreclinical
Canada
Lunenfeld-Tanenbaum Research InstituteLunenfeld-Tanenbaum Research Institute
10 Aug 2020
BRAF V600E Mutation-Positive MelanomaPreclinical
Canada
Ontario Institute for Cancer ResearchOntario Institute for Cancer Research
10 Aug 2020
BRAF V600E Mutation-Positive MelanomaPreclinical
Canada
University of TorontoUniversity of Toronto
10 Aug 2020
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Approval

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Regulation

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