100 Clinical Results associated with MGluR2 Negative Allosteric Modulators(Emory University)
100 Translational Medicine associated with MGluR2 Negative Allosteric Modulators(Emory University)
100 Patents (Medical) associated with MGluR2 Negative Allosteric Modulators(Emory University)
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Literatures (Medical) associated with MGluR2 Negative Allosteric Modulators(Emory University)10 Apr 2025·ACS Medicinal Chemistry Letters
6-Aryl Isoindolin-1-ones: Novel mGluR2 Negative Allosteric Modulators
Author: Li, Yinlong ; Liang, Steven H.
This highlight presents novel 6-aryl isoindolin-1-one derivatives that developed as negative allosteric modulators (NAMs) of metabotropic glutamate receptor 2 (mGluR2). Chemical synthesis and potency (IC50) data for both mGluR2 and mGluR3 are disclosed.
100 Deals associated with MGluR2 Negative Allosteric Modulators(Emory University)