Last update 20 Mar 2025

MAGE-A1-specific T cell receptor-transduced autologous T-cell therapy (SignalOne Bio)

Overview

Basic Info

Drug Type
T-lymphocyte cell therapy
Synonyms
FHMagIC TCRT cell therapy, MAGEA1specific T cell receptortransduced autologous CD8+ and CD4+ Tcells
Target-
Action-
Mechanism
Immunologic cytotoxicity, T lymphocyte replacements
Therapeutic Areas
NeoplasmsRespiratory DiseasesSkin and Musculoskeletal Diseases+ [1]
Active Indication-
Inactive Indication
Breast CancerNon-Small Cell Lung CancerUrogenital Neoplasms
Originator Organization
SignalOne Bio
Active Organization-
Inactive Organization
Fred Hutchinson Cancer Research CenterFred Hutchinson Cancer Research CenterSignalOne Bio
Drug Highest PhasePendingPhase 1/2
First Approval Date-
Regulation-
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Related

100 Clinical Results associated with MAGE-A1-specific T cell receptor-transduced autologous T-cell therapy (SignalOne Bio)
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100 Translational Medicine associated with MAGE-A1-specific T cell receptor-transduced autologous T-cell therapy (SignalOne Bio)
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100 Patents (Medical) associated with MAGE-A1-specific T cell receptor-transduced autologous T-cell therapy (SignalOne Bio)
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100 Deals associated with MAGE-A1-specific T cell receptor-transduced autologous T-cell therapy (SignalOne Bio)
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Urogenital NeoplasmsPhase 2
United States
SignalOne Bio
07 Mar 2021
Non-Small Cell Lung CancerPhase 2
United States
SignalOne Bio
02 Mar 2021
Breast CancerPhase 2
United States
SignalOne Bio
21 Feb 2021
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Clinical Result

Indication
Phase
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Deal

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Clinical Trial

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Approval

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Regulation

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