Last update 16 Jul 2025

EPD-301

Overview

Basic Info

Drug Type
Proteolysis-targeting chimeras (PROTAC)
Synonyms
EPD 301, EPD301, GX-BP1
+ [1]
Target
SOX2
Action
degraders
Mechanism
SOX2 degraders(SRY-box transcription factor 2 degraders)
Therapeutic Areas
NeoplasmsRespiratory Diseases
Active Indication
squamous cell lung carcinomaNeoplasms
Inactive Indication-
Originator Organization
EPD Biotherapeutics, Inc.
Active Organization
EPD Biotherapeutics, Inc.Genexine, Inc.Genexine, Inc.
Inactive Organization
Takeda Pharmaceutical Co., Ltd.Takeda Pharmaceutical Co., Ltd.
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with EPD-301
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100 Translational Medicine associated with EPD-301
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100 Patents (Medical) associated with EPD-301
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100 Deals associated with EPD-301
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
squamous cell lung carcinomaPreclinical
South Korea
Takeda Pharmaceutical Co., Ltd.Takeda Pharmaceutical Co., Ltd.
16 Oct 2024
squamous cell lung carcinomaPreclinical
South Korea
Genexine, Inc.Genexine, Inc.
16 Oct 2024
NeoplasmsPreclinical
South Korea
EPD Biotherapeutics, Inc.
08 Apr 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Core Patent

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Clinical Trial

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Approval

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Regulation

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