Last update 31 Jul 2025

GENA-111-AF

Overview

Basic Info

Drug Type
Antibody drug conjugate (ADC)
Synonyms
GENA-111-auristatin F
Target
BCAM x Tubulin
Action
inhibitors
Mechanism
BCAM inhibitors(basal cell adhesion molecule (Lutheran blood group) inhibitors), Tubulin inhibitors
Therapeutic Areas
NeoplasmsSkin and Musculoskeletal Diseases
Active Indication
Skin Neoplasms
Inactive Indication
Squamous Cell Carcinoma
Originator Organization
Debiopharm International SADebiopharm International SAGenome & Co.Genome & Co.
Active Organization
Debiopharm Research & Manufacturing SADebiopharm International SADebiopharm International SAGenome & Co.Genome & Co.
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Structure/Sequence

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Related

100 Clinical Results associated with GENA-111-AF
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100 Translational Medicine associated with GENA-111-AF
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100 Patents (Medical) associated with GENA-111-AF
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100 Deals associated with GENA-111-AF
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Skin NeoplasmsPreclinical
South Korea
Genome & Co.Genome & Co.
15 Jun 2022
Skin NeoplasmsPreclinical
Switzerland
Debiopharm Research & Manufacturing SA
15 Jun 2022
Skin NeoplasmsPreclinical
Switzerland
Debiopharm International SADebiopharm International SA
15 Jun 2022
NeoplasmsPreclinical
South Korea
Genome & Co.Genome & Co.
11 Apr 2022
Squamous Cell CarcinomaPreclinical
South Korea
Genome & Co.Genome & Co.
11 Apr 2022
Squamous Cell CarcinomaPreclinical
Switzerland
Debiopharm International SADebiopharm International SA
11 Apr 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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