Last update 05 Dec 2025

YYB-103

Overview

Basic Info

Drug Type
Universal CAR-T
Synonyms
CLM-103, YYB 103, YYB103
+ [1]
Target
IL-13Rα2
Action
inhibitors
Mechanism
IL-13Rα2 inhibitors(Interleukin-13 receptor subunit alpha-2 inhibitors), Gene transference(Gene transference), T lymphocyte replacements
Therapeutic Areas
NeoplasmsNervous System DiseasesOther Diseases
Active Indication
Glioblastoma Multiforme
Inactive Indication
Amyotrophic Lateral SclerosisRecurrent Malignant Glioma
Originator Organization
Yooyoung Pharm Co. Ltd.Yooyoung Pharm Co. Ltd.
Active Organization
Cell Lab MedCell Lab Med
Inactive Organization
Yooyoung Pharm Co. Ltd.Yooyoung Pharm Co. Ltd.
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with YYB-103
NCT05540873
/ Unknown statusPhase 1
A Single-center, Single-arm, Open-label Phase 1 Clinical Trial to Assess the Safety and Tolerability of YYB-103, IL13Rα2 Targeted Chimeric Antigen Receptor-T Cell (CAR-T) in Treating Patients With Refractory or Recurrent Malignant Glioma
100 Clinical Results associated with YYB-103
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100 Translational Medicine associated with YYB-103
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100 Patents (Medical) associated with YYB-103
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100 Deals associated with YYB-103
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Amyotrophic Lateral SclerosisNDA/BLA
South Korea
Yooyoung Pharm Co. Ltd.Yooyoung Pharm Co. Ltd.
-
Glioblastoma MultiformePhase 1
South Korea
Cell Lab MedCell Lab Med
18 Jul 2022
Recurrent Malignant GliomaPhase 1
South Korea
Cell Lab MedCell Lab Med
18 Jul 2022
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Clinical Result

Indication
Phase
Evaluation
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Core Patent

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Clinical Trial

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Approval

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Regulation

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