Last update 26 Jan 2025

VH-2C-6C-Dab#1

Overview

Basic Info

Drug Type
Proteolysis-targeting chimeras (PROTAC)
Synonyms
VH-2C-6C-Dab#1
Target
BRAF V600E
Mechanism
BRAF V600E inhibitors
Therapeutic Areas
NeoplasmsSkin and Musculoskeletal Diseases
Active Indication
BRAF V600E Mutation-Positive Melanoma
Inactive Indication-
Originator Organization
University of TorontoUniversity of Toronto
Active Organization
Ontario Institute for Cancer ResearchOntario Institute for Cancer ResearchLunenfeld-Tanenbaum Research InstituteLunenfeld-Tanenbaum Research InstituteUniversity of TorontoUniversity of Toronto
Inactive Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC55H65F3N10O7S3
InChIKeyXIEAIGUZMCJELK-YZDWGWATSA-N
CAS Registry-

Related

100 Clinical Results associated with VH-2C-6C-Dab#1
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100 Translational Medicine associated with VH-2C-6C-Dab#1
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100 Patents (Medical) associated with VH-2C-6C-Dab#1
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100 Deals associated with VH-2C-6C-Dab#1
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
BRAF V600E Mutation-Positive MelanomaPreclinical
CA
Ontario Institute for Cancer ResearchOntario Institute for Cancer Research
10 Aug 2020
BRAF V600E Mutation-Positive MelanomaPreclinical
CA
Lunenfeld-Tanenbaum Research InstituteLunenfeld-Tanenbaum Research Institute
10 Aug 2020
BRAF V600E Mutation-Positive MelanomaPreclinical
CA
University of TorontoUniversity of Toronto
10 Aug 2020
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Clinical Result

Indication
Phase
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Phase
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Deal

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Approval

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Regulation

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