Last update 08 May 2025

TT-00920

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Target
PDE9A
Action
inhibitors
Mechanism
PDE9A inhibitors(Phosphodiesterase 9A inhibitors)
Therapeutic Areas
Cardiovascular DiseasesCongenital DisordersHemic and Lymphatic Diseases+ [1]
Active Indication
Chronic heart failureAnemia, Sickle Cell
Inactive Indication-
Originator Organization
TransThera Sciences (Nanjing), Inc.TransThera Sciences (Nanjing), Inc.
Active Organization
TransThera Sciences (Nanjing), Inc.TransThera Sciences (Nanjing), Inc.
Inactive Organization-
License Organization-
Drug Highest PhaseIND Approval
First Approval Date-
Regulation-
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Related

4
Clinical Trials associated with TT-00920
NCT05355129
/ CompletedPhase 1
A Phase I, Randomized, Double-blind, Placebo-controlled, Ascending Single Dose and Multiple Dose Study of TT-00920 in Healthy Subjects
CTR20211578
/ CompletedPhase 1
TT-00920在健康受试者中随机、双盲、安慰剂对照、单次和多次给药剂量递增的I期临床试验
[Translation] A randomized, double-blind, placebo-controlled, single- and multiple-dose escalation phase I clinical trial of TT-00920 in healthy subjects
NCT05043792
/ CompletedPhase 1
A Phase I, Randomized, Double-Blind, Placebo-Controlled, Multiple-Ascending Dose Study of TT-00920 in Healthy Subjects
100 Clinical Results associated with TT-00920
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100 Translational Medicine associated with TT-00920
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100 Patents (Medical) associated with TT-00920
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100 Deals associated with TT-00920
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Chronic heart failureIND Approval
United States
TransThera Sciences (Nanjing), Inc.TransThera Sciences (Nanjing), Inc.
17 Dec 2019
Anemia, Sickle CellPreclinical
China
TransThera Sciences (Nanjing), Inc.TransThera Sciences (Nanjing), Inc.
26 Aug 2021
Heart FailureDiscovery
China
TransThera Sciences (Nanjing), Inc.TransThera Sciences (Nanjing), Inc.
01 Nov 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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