Last update 06 Dec 2025

GT-729

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
GT 729, GT729
Target
EAAT2
Action
modulators
Mechanism
EAAT2 modulators(solute carrier family 1 member 2 modulators)
Therapeutic Areas
Immune System DiseasesOther DiseasesNervous System Diseases
Active Indication
Chronic graft-versus-host diseaseCentral Nervous System Diseases
Inactive Indication-
Originator Organization
The Wistar InstituteThe Wistar Institute
Active Organization
Zhuhai Grit Biotechnology Co., Ltd.Zhuhai Grit Biotechnology Co., Ltd.The Wistar InstituteThe Wistar Institute
Inactive Organization-
License Organization-
Drug Highest PhaseEarly Phase 1
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC30H31N7O3
InChIKeyVQWZMSSPDDDVHX-UHFFFAOYSA-N
CAS Registry460328-20-5

Related

1
Clinical Trials associated with GT-729
NCT07253259
/ RecruitingEarly Phase 1
A Clinical Study Evaluating the Safety and Efficacy of GT729 Universal Cell Injection in the Treatment of Refractory or Relapsed Chronic Graft-versus-host Disease (cGVHD)
100 Clinical Results associated with GT-729
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100 Translational Medicine associated with GT-729
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100 Patents (Medical) associated with GT-729
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100 Deals associated with GT-729
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Chronic graft-versus-host diseasePhase 1
China
Zhuhai Grit Biotechnology Co., Ltd.Zhuhai Grit Biotechnology Co., Ltd.
01 Dec 2025
Central Nervous System DiseasesDiscovery
United States
The Wistar InstituteThe Wistar Institute
16 Apr 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Clinical Trial

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Approval

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Regulation

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