Delving into the Latest Updates on Cholecalciferol Chloesterol with Synapse

Overview

Basic Info

Drug Type

Small molecule drug

Synonyms

英康利

Target-

Mechanism-

Therapeutic Areas

Endocrinology and Metabolic DiseaseSkin and Musculoskeletal Diseases

Active Indication

OsteoporosisRickets

Inactive Indication-

Originator Organization

Suzhou First Pharmaceutical Co., Ltd.

Active Organization

Suzhou First Pharmaceutical Co., Ltd.

Inactive Organization-

Drug Highest PhaseApproved

First Approval Date

CN (01 Jan 1982),

OsteoporosisRickets

Regulation-

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Structure

Molecular FormulaC28H46O

InChIKeyDIPPFEXMRDPFBK-JPWDPSJFSA-N

CAS Registry511-28-4

Vitamin D receptors are expressed in activated different immune cells. It is not known, which immune cell type is targeted by exogenous vitamin D. Here, vitamin D-deficient individuals will receive once 100.000 I.U. vitamin D3 either intramuscular or subcutaneous in a double-blind placebo controlled setting. Immune cells will be monitored from the blood over time.

Start Date01 Feb 2013

Sponsor / Collaborator

Charité - Universitätsmedizin Berlin

100 Clinical Results associated with Cholecalciferol Chloesterol

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100 Translational Medicine associated with Cholecalciferol Chloesterol

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100 Patents (Medical) associated with Cholecalciferol Chloesterol

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2

Literatures (Medical) associated with Cholecalciferol Chloesterol

25 Jan 1971·FEBS LettersQ3 · BIOLOGY

The metabolism of cholesterol by the echinoderms Aterias rubens and Solaster papposus

Q3 · BIOLOGY

Article

Author: L.J. Goad ; A.G. Smith

When 4-14C-labeled cholesterol (I) was injected into the echinoderm A. rubens, it was metabolized to cholest-7-enol, 5α-cholestanol, 7α,8α-epoxycholestanol, and 5α,6α-epoxycholestanol.Similar results were obtained following injection of S. papposus with 4-14C-labeled I for 9 days.

01 Jan 1971·The Kurume Medical Journal

THE EFFECT OF ADENOSINE AND B2-TETRABUTYRATE ON HIGH LIPID BLOOD ANIMALS

Article

Author: Tadashi Arima ; Seiichiro Yamasaki

Rabbits were fed 100 g/day of a standard ration containing 1% chloesterol.One group of 5 was supplemented with 20 mg/kg/day of adenosine and 8.5 mg/day vitamin B2 tetrabutyrate.Another group was supplemented with 8.5 mg/day of vitamin B2 tetrabutyrate, and a third group was given only the cholesterol-fortified ration.After 6-weeks feeding the change in vitamin B2 quantity in liver, kidney, and heart was measured and total cholesterol, phospholipid triglyceride, lipid peroxide, and protein were determined in the blood.Both adenosine and vitamin B2-tetrabutyrate treatment significantly raised vitamin B2 levels over controls, the joint administration giving higher levels than with vitamin B2 tetrabutyrate alone.

100 Deals associated with Cholecalciferol Chloesterol

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