Last update 23 May 2025

Amlodipine Besylate/Chlorthalidone/Telmisartan

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Amlodipine/chlortalidone/telmisartan, Amlodipine/telmisartan/chlortalidone, Chlortalidone/amlodipine/telmisartan
+ [8]
Target
AT1R x NCC x VDCCs
Action
antagonists, inhibitors, blockers
Mechanism
AT1R antagonists(Angiotensin II Receptor Type 1 antagonists), NCC inhibitors(Thiazide-sensitive sodium-chloride cotransporter inhibitors), VDCCs blockers(Voltage-gated calcium channel blockers)
Therapeutic Areas
Cardiovascular Diseases
Active Indication
Hypertension
Inactive Indication
Essential Hypertension
Originator Organization
Yuhan Corp.
Active Organization
Yuhan Corp.
Inactive Organization-
License Organization-
Drug Highest PhaseApproved
First Approval Date
South Korea (23 Aug 2019),
Hypertension
Regulation-
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Structure/Sequence

Molecular FormulaC14H11ClN2O4S
InChIKeyJIVPVXMEBJLZRO-UHFFFAOYSA-N
CAS Registry77-36-1
View All Structures (3)

Related

5
Clinical Trials associated with Amlodipine Besylate/Chlorthalidone/Telmisartan
NCT06041529
/ RecruitingPhase 4
An Open-Label, Superiority, Randomized, Comparative Study to Evaluate the Efficacy and Safety of Telmisartan, Amlodipine, and Chlorthalidone Fixed-Dose Combination Versus Telmisartan, Amlodipine, and Hydrochlorothiazide in Elderly Patients with Essential Hypertension Uncontrolled by Telmisartan and Amlodipine Combinations
NCT06282549
/ Active, not recruitingNot Applicable
A Prospective Long-term Cohort Study to Identify the Predictive Model of Cardiocerebrovascular Risk Factors in Elderly Patients with More Than Three Antihypertensive Agents in Patients with Essential Hypertension in Korea
NCT03662620
/ CompletedPhase 1
A Randomized, Open-label, Single Dose, Replicate Crossover Clinical Trial to Compare the Safety and Pharmacokinetics of YH22162 in Healthy Volunteers
100 Clinical Results associated with Amlodipine Besylate/Chlorthalidone/Telmisartan
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100 Translational Medicine associated with Amlodipine Besylate/Chlorthalidone/Telmisartan
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100 Patents (Medical) associated with Amlodipine Besylate/Chlorthalidone/Telmisartan
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100 Deals associated with Amlodipine Besylate/Chlorthalidone/Telmisartan
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Hypertension
South Korea
Yuhan Corp.
23 Aug 2019
Developing
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IndicationHighest PhaseCountry/LocationOrganizationDate
Essential HypertensionPhase 3
United States
Yuhan Corp.
01 Dec 2015
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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