Last update 30 Aug 2025

ZW-38

Overview

Basic Info

Drug Type
Bispecific T-cell Engager (BiTE)
Synonyms
ZW38
Target
CD19 x CD3
Action
inhibitors, stimulants
Mechanism
CD19 inhibitors(B-lymphocyte antigen CD19 inhibitors), CD3 stimulants(T cell surface glycoprotein CD3 stimulants)
Therapeutic Areas
NeoplasmsImmune System DiseasesHemic and Lymphatic Diseases
Active Indication-
Inactive Indication
B-Cell LymphomaCD19 positive B-Cell Lymphoma
Originator Organization
Zymeworks, Inc.
Active Organization-
Inactive Organization
Zymeworks, Inc.
License Organization-
Drug Highest PhasePendingPreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with ZW-38
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100 Translational Medicine associated with ZW-38
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100 Patents (Medical) associated with ZW-38
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100 Deals associated with ZW-38
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
B-Cell LymphomaPreclinical-
Zymeworks, Inc.
02 Dec 2016
CD19 positive B-Cell LymphomaPreclinical
Canada
Zymeworks, Inc.
20 May 2015
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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