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Last update 08 May 2025

Phenylpropanol

Last update 08 May 2025

Overview

R&D Status

Clinical Result

Translational Medicine

Overview

Basic Info

Drug Type

Small molecule drug

Synonyms

Phenylpropanol (JAN)

Target-

Action-

Mechanism-

Therapeutic Areas

Digestive System Disorders

Active Indication

Biliary Tract DiseasesGastrointestinal Diseases

Inactive Indication-

Originator Organization-

Active Organization-

Inactive Organization-

License Organization-

Drug Highest PhaseApproved

First Approval Date-

Regulation-

Structure/Sequence

Molecular FormulaC9H12O

InChIKeyDYUQAZSOFZSPHD-UHFFFAOYSA-N

CAS Registry93-54-9

100 Clinical Results associated with Phenylpropanol

100 Translational Medicine associated with Phenylpropanol

100 Patents (Medical) associated with Phenylpropanol

2,847

Literatures (Medical) associated with Phenylpropanol

14 Apr 2025·ChemSusChem

Mild Aerobic Oxidation of Secondary Alcohols with Water Tolerant Cu(I) Catalyst

Article

Author: Eronen, Aleksi ; Heshmatnia, Faranak ; Install, Joseph ; Zupanc, Anže ; Repo, Timo ; Lagerspets, Emi

AbstractGreen, aerobic oxidation of secondary alcohols to ketones poses a significant synthetic challenge. To address this, we have developed a highly active (DPA)CuI/ABNO catalyst system capable of aerobically oxidizing a wide range of secondary alcohols, including benzylic and aliphatic derivatives, yielding the corresponding ketones with high yields. The unique feature of this Cu(I) catalyst is its high stability, even in the presence of water. We also prepared CuI from waste copper sources to enhance the system′s sustainability.

01 Apr 2025·Synlett

Borane-Catalyzed Divergent para and ortho C-Alkylation of Arylamines Using Benzylic Alcohols

Author: Hu, Hao-Lan ; Jiang, Yi-Jun ; Shi, Jianghuan ; Chen, Peng ; Niu, Yu-Dan ; Li, Meng-Yuan

AbstractA catalyst-controlled divergent alkylation of diarylamines with benzylic alcohols has been developed. A para C-alkylation of diarylamines could be achieved by using B(C6F5)3 as the catalyst, whereas ortho C-alkylation of diarylamines could be achieved by using HBF4·Et2O as the catalyst. The salient features of this transformation include readily available materials, a broad substrate scope, easily available catalysts, and simple and mild reaction conditions.

27 Mar 2025·The Journal of Physical Chemistry B

Linear-Limit Aging Times of Three Monoalcohols

Article

Author: Dyre, Jeppe C. ; Hecksher, Tina ; Gabriel, Jan Philipp

This paper presents data on the physical aging of three monoalcohols, 2-ethyl-1-butanol, 5-methyl-2-hexanol, and 1-phenyl-1-propanol. Aging is studied by monitoring the dielectric loss at a fixed frequency in the kHz range following temperature jumps of a few Kelvin's magnitude, starting from states of equilibrium. The three alcohols differ in Debye relaxation strength and how much the Debye process is separated from the α process. We first demonstrate that single-parameter aging describes all data well and proceed to utilize this fact to identify the linear-limit normalized aging relaxation functions. From the Laplace transform of these functions, the linear-limit aging loss-peak angular frequency defines the inverse of the linear aging relaxation time. This allows for a comparison to the temperature dependence of the Debye and α dielectric relaxation times of the three monoalcohols. We conclude that the aging response for 5-methyl-2-hexanol and 2-ethyl-1-butanol follows the α relaxation, not the Debye process; no firm conclusion can be reached for 1-phenyl-1-propanol because its Debye and α processes are too close to be reliably distinguished.

100 Deals associated with Phenylpropanol

External Link

KEGG	Wiki	ATC	Drug Bank
D01470	-	A	-

R&D Status

10 top approved records.

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Indication	Country/Location	Organization	Date
Biliary Tract Diseases	-	-	-
Gastrointestinal Diseases	-	-	-

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