Last update 08 May 2025

Napazimone

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
NQO1 substrate KTG Life Sciences
+ [2]
Action
modulators
Mechanism
NAD+ modulators(NAD(Nicotinamide adenine dinucleotide) modulators), NQO1 modulators(Quinone reductase 1 modulators)
Originator Organization
Active Organization
Inactive Organization
Drug Highest PhasePhase 3
First Approval Date-
RegulationOrphan Drug (European Union), Fast Track (United States)
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Structure/Sequence

Molecular FormulaC14H12N2O2
InChIKeyAJFWITSBVLLDCC-UHFFFAOYSA-N
CAS Registry1800405-30-4

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Mitochondrial DiseasesPhase 3--
Kearns-Sayre SyndromePhase 2
Denmark
13 Dec 2022
Kearns-Sayre SyndromePhase 2
United Kingdom
13 Dec 2022
Kearns-Sayre SyndromePhase 2
Spain
13 Dec 2022
Kearns-Sayre SyndromePhase 2
Belgium
13 Dec 2022
Kearns-Sayre SyndromePhase 2
France
13 Dec 2022
Kearns-Sayre SyndromePhase 2
United States
13 Dec 2022
MELAS SyndromePhase 2
France
13 Dec 2022
MELAS SyndromePhase 2
United Kingdom
13 Dec 2022
MELAS SyndromePhase 2
Spain
13 Dec 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Approval

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Regulation

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