Last update 25 Oct 2025

TQB-3558

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
CT-3417, TQB 3558, TQB3558
Target
TrkA x TrkB x TrkC
Action
antagonists, inhibitors
Mechanism
TrkA antagonists(Nerve growth factor receptor Trk-A antagonists), TrkB inhibitors(Neurotrophic tyrosine kinase receptor type 2 inhibitors), TrkC inhibitors(Neurotrophic tyrosine kinase receptor type 3 inhibitors)
Therapeutic Areas
Neoplasms
Active Indication-
Inactive Indication
Advanced Malignant Solid Neoplasm
Originator Organization
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Active Organization-
Inactive Organization
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
License Organization
Centaurus Biopharma Co LtdCentaurus Biopharma Co LtdChia Tai Tianqing Pharmaceutical Group Co., Ltd.Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Drug Highest PhaseDiscontinuedPhase 1
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with TQB-3558
NCT04408079
/ Unknown statusPhase 1
A Phase I, Open-label, Dose Escalation and Expansion Study to Evaluate the Tolerance, Efficacy and Pharmacokinetics of TQB3558 Tablets
CTR20200697
/ TerminatedPhase 1
TQB3558片耐受性、有效性和药代动力学Ⅰ期临床试验
[Translation] Phase I clinical trial of tolerability, efficacy and pharmacokinetics of TQB3558 tablets
100 Clinical Results associated with TQB-3558
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100 Translational Medicine associated with TQB-3558
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100 Patents (Medical) associated with TQB-3558
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100 Deals associated with TQB-3558
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 1
China
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
22 Jun 2020
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Clinical Result

Indication
Phase
Evaluation
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Clinical Trial

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Approval

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Regulation

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