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Last update 16 May 2025
Clonidine/Naltrexone
Last update 16 May 2025
Overview
Basic Info
Drug Type Small molecule drug |
Synonyms ATNC 05, ATNC-05, ATNC05 |
Target |
Action agonists, antagonists |
Mechanism ADRA2 agonists(Adrenergic receptors alpha-2 agonists), Opioid receptors antagonists(Opioid receptors antagonists) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
License Organization- |
Drug Highest PhaseDiscontinuedPhase 2/3 |
First Approval Date- |
RegulationOrphan Drug (United States) |
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Structure/Sequence
Molecular FormulaC20H24ClNO4 |
InChIKeyRHBRMCOKKKZVRY-ITLPAZOVSA-N |
CAS Registry16676-29-2 |
View All Structures (2)
Related
2
Clinical Trials associated with Clonidine/NaltrexoneNCT01920087
Phase II Double Blind, Randomized, Placebo Controlled, Safety and Efficacy Study of ATNC05 in Patients With Atypical Facial Pain With an Open-Label Extension Phase for Nonresponders
NCT01415895
A Proof-of-Concept, Randomized, Double-Blind and Placebo Controlled Clinical Trial With Naltrexone and Clonidine Combination (ATNC05) Compared With Placebo in the Treatment of Chronic Back Pain
100 Clinical Results associated with Clonidine/Naltrexone
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100 Translational Medicine associated with Clonidine/Naltrexone
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100 Patents (Medical) associated with Clonidine/Naltrexone
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100 Deals associated with Clonidine/Naltrexone
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Facial Pain | Phase 3 | United States | 01 Mar 2014 | |
| Neuralgia | Phase 3 | United States | 01 Mar 2014 | |
| Trigeminal Neuralgia | Phase 3 | United States | 01 Mar 2014 | |
| Low Back Pain | Phase 2 | United States | 01 Jul 2011 | |
| Neck Pain | Phase 2 | United States | 01 Jul 2011 |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
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Regulation
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