Last update 11 Oct 2025

Brompheniramine Maleate/Dextromethorphan Hydrobromide/Pseudoephedrine Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
BROMFED-DM, Bromanate dm, DIMETANE-DX
Target
H1 receptor x NMDA receptor x α-adrenergic receptor
Action
antagonists, agonists
Mechanism
H1 receptor antagonists(Histamine H1 receptor antagonists), NMDA receptor antagonists(Glutamate [NMDA] receptor antagonists), α-adrenergic receptor agonists(Alpha adrenergic receptor agonists)
Therapeutic Areas
Infectious DiseasesOtorhinolaryngologic DiseasesRespiratory Diseases
Active Indication-
Inactive Indication
CoughNasal ObstructionRespiratory Tract Infections
Originator Organization
A.H. Robins Co., Inc.
Active Organization-
Inactive Organization
A.H. Robins Co., Inc.
License Organization-
Drug Highest PhaseWithdrawn
First Approval Date
United States (24 Aug 1984),
CoughNasal ObstructionRespiratory Tract Infections
Regulation-
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Structure/Sequence

Molecular FormulaC10H16ClNO
InChIKeyBALXUFOVQVENIU-KXNXZCPBSA-N
CAS Registry345-78-8
View All Structures (3)

Related

100 Clinical Results associated with Brompheniramine Maleate/Dextromethorphan Hydrobromide/Pseudoephedrine Hydrochloride
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100 Translational Medicine associated with Brompheniramine Maleate/Dextromethorphan Hydrobromide/Pseudoephedrine Hydrochloride
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100 Patents (Medical) associated with Brompheniramine Maleate/Dextromethorphan Hydrobromide/Pseudoephedrine Hydrochloride
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100 Deals associated with Brompheniramine Maleate/Dextromethorphan Hydrobromide/Pseudoephedrine Hydrochloride
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External Link

KEGGWikiATCDrug Bank
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N07XX59R06AB51R01BA52
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R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Cough
United States
A.H. Robins Co., Inc.
24 Aug 1984
Nasal Obstruction
United States
A.H. Robins Co., Inc.
24 Aug 1984
Respiratory Tract Infections
United States
A.H. Robins Co., Inc.
24 Aug 1984
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Clinical Trial

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Approval

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Regulation

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